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Started 10 years ago by lm6i8d4177

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 the use of drugs targeting the situation is worse than not. The study was published in 2009,nike air max outlet, Professor Shepherd former President of the International Association for the Study of lung cancer (IASLC) wrote that the study is especially "in the history of cancer research called one of the landmark studies, the establishment of a new standard for the treatment of EGFR gene mutations in lung cancer."In Western countries intend to destroy Iressa when, in 2006, Wu Yilong and Professor Mo Shujin Chinese University of Hong Kong and seven clinical scientists led from Japan,air jordan shop, Thailand, launched "Iressa (gefitinib) Pan Asian research program. " They took an internationally recognized research mode.

 the median overall survival of 22 months.This study is referred to as the IPASS (Iressa Pan-Asia Study, Iressa Pan-Asia Study), published in 2009,nike free run italia, more than a thousand cases of clinical trials have confirmed Iressa for patients with EGFR mutations effective rate of 70%.Why look before drugs ineffective, because there is no specific group of people against. And let the drug effective, you must first check the EGFR gene mutations. "The results came out, it laid the pattern of lung cancer after research and development,zanotti, we must do first to lung cancer gene mutation, according to genetic mutations to determine treatment options." EVIDENCE of Chinese patients do genetic testing to get the same results, indicating that the conclusion is precise.This study shock lung cancer research academics, Professor Shepherd former President of the International Association for the Study of lung cancer (IASLC) particular author said the study is "the history of cancer research called one of the landmark studies,nike sito ufficiale, the establishment of a new standard for the treatment of EGFR gene mutations in lung cancer" It was named Outstanding (Exceptional) Paper International F1000 biomedical literature evaluation system.The latest idea is to drive the gene for tumor therapy the tumor to figure out first, then design treatment programs. "If even the 'culprit' did not understand the blind medication, blind treatment, then the effect of these drugs may even not as a placebo."This study is of great practical significance.According to 2012 World Health Organization data, the global incidence of lung cancer 1.825 million cases per year,basket louboutin, China had 653,000 cases, accounting for 35.8%. According to statistics, nearly 20 years may be due to social changes in lifestyle and environmental factors,nike sito ufficiale, the incidence of lung squamous cell ratio decreased,air jordan donna, the incidence of lung cancer increased significantly.Pulmonary a provincial health department chief physician Yang Jin remember.

 EVIDENCE noticed the news was mostly domestic research on lung cancer research stay in cytology, as tutor of doctoral students EVIDENCE make all men stop the hands of the subject,air max italia, into the activation of the EGFR gene mutation status of research.He recalled, also Iressa,outlet moncler, clinical research in Japan a few years ago with American counterparts research data discrepancies,nike free run online, Japan has 10% of the effect, and the United States lower. "At that time no one dared to say this, because if the drug has a different effect on different races,scarpe nike air max, will be considered racial discrimination, has aroused great controversy in the medical profession."EVIDENCE team by analyzing the Guangdong Provincial People's Hospital 145 cases and Beijing, Shanghai, Guangzhou and other six cooperative unit activated a total of 506 cases of lung cancer patients with EGFR gene mutation status found that EGFR Chinese people is "special" driver gene."The epidermal growth factor receptor in China, especially in East Asia population mutation rate is particularly high,scarpe nike air max, about 30% of all non-small cell lung cancer, while in the West the population is less than 10%,nike free run 3.0, which is a very big distinction. "The study was published in 2005, caused a sensation in the industry."Resurrection" of targeted drugsEVIDENCE found that when patients have EGFR mutations, the use of such targeted drug Iressa progression-free survival may be extended to 9.5 months; but if the patient does not have the mutation.

 for example, to the Guangdong Provincial People's Hospital, for example,air jordan, admitted 1500 cases per year of new lung cancer patients with non-small cell lung cancer and small cell lung cancer accounts for 80% -85% and 15% -20%,air jordan shop, respectively,outlet peuterey, of non- Small cell lung cancer is about 60 percent more lung cancer, and lung cancer patients have a 70 percent to find targets - driven gene.

 two groups of patients randomized, controlled efficacy to see the effect of Iressa and starch is not the same.In order to do this study, EVIDENCE brains. At that time a method of genetic testing in the world have not yet conclusive noisy, directly to do genetic testing has been greatly restricted. They used an innovative nobody used method worldwide - with clinicopathological features to patient selection, and chose the two most representative features: do not smoke and pathology adenocarcinoma,nike air max italia, there are these two characteristics The EGFR gene mutation is the most patient of people.EVIDENCE found that when patients have EGFR mutations, the use of such targeted drug Iressa progression-free survival may be extended to 9.5 months, significantly better than patients with chemotherapy alone; but if the patient does not have the mutation, the use of targeted drugs the situation is worse than not. Long-term follow-up analysis found that mutant EGFR-targeted treatment to patients.

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