<p> there is no compulsory certification.A Zhejiang pharmaceutical research director told the "Financial" reporter, some pharmaceutical companies in order to save costs in the drug approval procedures, to regulatory authorities to declare a higher-quality materials manufacturers entering the production chain,barbour pas cher, will replace the cheap, inferior quality manufacturers. And made even listed in the drug front,hollister, not normally be required to test again.China is a major exporter of raw materials and the production of drugs, but a serious shortage of materials research and development,barbour pas cher, new pharmaceutical excipients almost entirely dependent on imports.Zhang will be told the "Financial" reporter.</p>
<p> such as the emergence of one or more specific impurities, which will produce pharmacological effects of uncertainty in the environment, and thus a security risk.The US Food and Drug Administration (FDA) regulations, when generic drugs for approval, also need to declare the materials used in medicines,woolrich parka, and materials production enterprises manufacturing practice certificate (GMP) and inspection reports (COA),giuseppe zanotti femme, to provide analytical data.But China is not strict regulation of the excipients. 2006 introduction of the "medicinal materials production quality management standards".</p>
<p> quality control is not strictly the case that insufficient efficacy.Generics and active chemical components of the original drug should be the same. After the original drug patents expire, the molecular structure of active ingredients,zapatillas nike hombre, dosage and physicochemical properties will open. For example,louboutin femme, "Viagra" details of the active ingredients can even be found in Baidu Encyclopedia.However, these active ingredients can be successfully released on time in the human body, is the efficacy of the drugs play a key. Pill, when passing through the patient's digestive system, to be at the appropriate time disintegrate, dissolve, releasing the active ingredient,woolrich outlet, is absorbed from the gastrointestinal tract.This process is very particular: if it is too fast, too fast could lead to absorption of the active ingredient, the peak serum concentration is too high, side effects and efficacy lasting enough; if less speed, the active ingredient may be too late to completely dissolved was discharged,giuseppe zanotti homme, medicine Efficiency is not play.This process is necessary to rely on the use of materials and the production process of drugs.</p>
<p> which is a very core pharmaceutical research and development assets.In Germany, Bayer Aspirin produced, for example, Bayer has a unique formulation technology, which allows the drug after the patent expired still evade the challenge, because the domestic generic drug can not be achieved in the process so that the drug is dissolved in the gut only."Original drug manufacturers generally have multiple process patented formula." Vice-president of the China Pharmaceutical Quality Management Association MEET "financial" reporter, a new drug patent term is 20 years, and pharmaceutical companies in the compounds,louboutin femme pas cher, pharmaceutical raw materials patents expire After formulation process also has a patent will expire after a few years, a move that allows the use of patented drugs is extended deadline.In addition, pharmaceutical excipients and more play a key role. Excipients, most polymer materials, there is a certain molecular weight distribution, rather than a single component, which means that the content is difficult to use simple indicators detect it. Therefore, the same name accessories,hollister online, if manufactured by different companies,giubbino peuterey uomo, product differences can be large. There are some varieties of accessories.</p>
<p> many domestic pharmaceutical companies to use generic drugs with different accessories original drug production,moncler homme paris, which is one of the reasons leading to generic drugs and the original drug efficacy differences.September 2014 blockbuster "poison capsule" incident on the incident in the accessories. Case in Zhejiang, a medicinal materials production with industrial gelatin pharmaceutical capsule into the pharmaceutical companies, resulting in 90 million chromium exceeded poison capsule into the market."Poison capsule" event is of extreme events lax control accessories. Since the vast majority of technology and materials leads to inadequate efficacy of generic drugs, the production and circulation of drugs is inefficient or ineffective drugs. While this drug will not cause harm,barbour soldes, but the efficacy is not enough, only delay the timing of treatment,zanotti pas cher, there may prolong the suffering of patients, duration.For example,tom ford shoes, people with mental disorders disease need regular clozapine to make a stable condition under control,peuterey prezzi, in conjunction with other treatment methods to implement treatment. Clozapine itself has a side effect, there will be a reduced white blood cell symptoms in patients taking. Veteran of the pharmaceutical industry to the "financial" reporters that they found in the study, patients taking clozapine in domestic,scarpe hogan outlet, rarely leukopenia case, indicating the drug's efficacy is insufficient. Mental disorders disease can not be helped if effective drugs, some people will have a tendency to violent attacks, and even suicide.Regulations and Registration Department director by the spring greenery Pharmaceutical Group Na told the "Financial" reporter, wide time window for drug treatment, if the efficacy of the drug itself is not enough.</p>
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